Clinical guidelines for testing for heritable thrombophilia
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چکیده
منابع مشابه
Clinical guidelines for testing for heritable thrombophilia.
Trevor Baglin, Elaine Gray, Mike Greaves, Beverley J. Hunt, David Keeling, Sam Machin, Ian Mackie, Mike Makris, Tim Nokes, David Perry, R. C. Tait, Isobel Walker and Henry Watson Addenbrooke’s Hospital, Cambridge, NIBSC, South Mimms, University of Aberdeen, Aberdeen, Guy’s and St Thomas’, London, Churchill Hospital, Oxford, University College Hospital, London, Royal Hallamshire Hospital, Sheffi...
متن کاملTesting for thrombophilia: clinical update.
British Journal of General Practice, February 2014 e120 baCKGROUND Thrombophilia describes inherited and acquired prothrombotic states which predispose to venous, but not arterial thromboembolism. The heritable states are of limited clinical significance in primary care and while they may underlie a patient’s presentation with deep venous thrombosis (DVT) or pulmonary embolism (PE) of uncertain...
متن کاملGuidelines for the management of thrombophilia
JD Cavenagh, BT Colvin Summary Although there are numerous risk factors for venous thromboembolic disease, the term 'thrombophilia' refers only to those familial or acquired disorders of the haemostatic system that result in an increased risk of thrombosis. The inherited thrombophilias include antithrombin III deficiency, resistance to activated protein C (factor V Leiden), protein C and protei...
متن کاملPharmacogenetic testing: time for clinical practice guidelines.
Our knowledge regarding genetic factors that affect drug effectiveness and adverse drug reactions is continuously increasing, and a growing number of pharmacogenetic gene– drug interactions are included in drug labels. Nevertheless, the uptake of this important information into clinical practice has been minimal. The development of concise, evidence-based clinical practice guidelines (CPGs) on ...
متن کاملHeritable Thrombophilia and Pregnancy Associated Thrombosis.
Venous thromboembolism VTE is the major cause of morbidity and mortality in pregnant woman in industrialized countries. VTE is said to occur at the rate of about 1 per 1000 pregnancies[1,2]. It is important to note that the frequency of asymptomatic DVT is probably not negligible specially in multiparity women as shown by the results of the Sirius Study in which multiparity was found to be a ri...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2010
ISSN: 0007-1048,1365-2141
DOI: 10.1111/j.1365-2141.2009.08022.x